STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AU072_15020Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)    
Predicted Functional Partners:
AU072_11560
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.991
AU072_04800
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.986
AU072_24115
Alpha-ketoglutarate decarboxylase.
 
 0.986
AU072_02045
Dihydrolipoyl dehydrogenase.
  
 
 0.980
AU072_03515
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component.
  
 0.978
AU072_11570
Pyruvate dehydrogenase E1 component alpha subunit pdhA.
    
 0.935
AU072_06285
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.924
AU072_12720
Acetolactate synthase 3 regulatory subunit.
     
 0.913
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
   
 
 0.911
AU072_01010
Oxidoreductase subunit alpha.
     
 0.910
Your Current Organism:
Mycolicibacterium novocastrense
NCBI taxonomy Id: 59813
Other names: CIP 105546, DSM 44203, JCM 18114, M. novocastrense, Mycobacterium novocastrense, Mycobacterium sp. GA-2613, Mycobacterium sp. GA-2617, Mycobacterium sp. GA-2945b, strain 73
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