| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KTR97943.1 | lapA | NS375_18115 | NS375_12755 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.655 |
| KTR97943.1 | seqA | NS375_18115 | NS375_06545 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replication initiation regulator SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.509 |
| KTR97943.1 | sprT | NS375_18115 | NS375_00560 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SprT family. | 0.513 |
| KTR98621.1 | lapA | NS375_14485 | NS375_12755 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.676 |
| KTR98621.1 | proQ | NS375_14485 | NS375_05340 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Prop expression regulator; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.756 |
| KTR98621.1 | rseA | NS375_14485 | NS375_09915 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | 0.723 |
| KTR98621.1 | seqA | NS375_14485 | NS375_06545 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replication initiation regulator SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.688 |
| KTR98621.1 | sprT | NS375_14485 | NS375_00560 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SprT family. | 0.552 |
| KTS01621.1 | KTS01623.1 | NS375_00555 | NS375_00565 | D-galactose transporter GalP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | DNA-specific endonuclease I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.432 |
| KTS01621.1 | sprT | NS375_00555 | NS375_00560 | D-galactose transporter GalP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SprT family. | 0.586 |
| KTS01623.1 | KTS01621.1 | NS375_00565 | NS375_00555 | DNA-specific endonuclease I; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-galactose transporter GalP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | 0.432 |
| KTS01623.1 | KTS01624.1 | NS375_00565 | NS375_00570 | DNA-specific endonuclease I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | 0.642 |
| KTS01623.1 | sprT | NS375_00565 | NS375_00560 | DNA-specific endonuclease I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SprT family. | 0.644 |
| KTS01624.1 | KTS01623.1 | NS375_00570 | NS375_00565 | 16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | DNA-specific endonuclease I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.642 |
| KTS01624.1 | sprT | NS375_00570 | NS375_00560 | 16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SprT family. | 0.552 |
| lapA | KTR97943.1 | NS375_12755 | NS375_18115 | Membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.655 |
| lapA | KTR98621.1 | NS375_12755 | NS375_14485 | Membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.676 |
| lapA | proQ | NS375_12755 | NS375_05340 | Membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Prop expression regulator; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.732 |
| lapA | rseA | NS375_12755 | NS375_09915 | Membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | 0.762 |
| lapA | rseB | NS375_12755 | NS375_09920 | Membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Anti-sigma E factor; Periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.691 |