| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KTR97273.1 | KTR99924.1 | NS375_20715 | NS375_08560 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.534 |
| KTR97273.1 | KTS01414.1 | NS375_20715 | NS375_03205 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.502 |
| KTR97273.1 | cobA | NS375_20715 | NS375_14390 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CysG; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.930 |
| KTR97273.1 | cysG | NS375_20715 | NS375_16975 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.927 |
| KTR97273.1 | hemA | NS375_20715 | NS375_03190 | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.749 |
| KTR99924.1 | KTR97273.1 | NS375_08560 | NS375_20715 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.534 |
| KTR99924.1 | KTS01414.1 | NS375_08560 | NS375_03205 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.679 |
| KTR99924.1 | cobA | NS375_08560 | NS375_14390 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CysG; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.534 |
| KTR99924.1 | cysG | NS375_08560 | NS375_16975 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.534 |
| KTR99924.1 | lolB | NS375_08560 | NS375_03185 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.709 |
| KTS01414.1 | KTR97273.1 | NS375_03205 | NS375_20715 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sirohydrochlorin ferrochelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.502 |
| KTS01414.1 | KTR99924.1 | NS375_03205 | NS375_08560 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.679 |
| KTS01414.1 | KTS01415.1 | NS375_03205 | NS375_03210 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.840 |
| KTS01414.1 | cobA | NS375_03205 | NS375_14390 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CysG; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.502 |
| KTS01414.1 | cysG | NS375_03205 | NS375_16975 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.502 |
| KTS01414.1 | hemA | NS375_03205 | NS375_03190 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.671 |
| KTS01414.1 | kdsA | NS375_03205 | NS375_03215 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-dehydro-3-deoxyphosphooctonate aldolase; Catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | 0.719 |
| KTS01414.1 | lolB | NS375_03205 | NS375_03185 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. | 0.569 |
| KTS01414.1 | prfA | NS375_03205 | NS375_03195 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.807 |
| KTS01414.1 | prmC | NS375_03205 | NS375_03200 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.880 |