| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KTR99302.1 | KTR99303.1 | NS375_09855 | NS375_09860 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family. | 0.909 |
| KTR99302.1 | KTS01597.1 | NS375_09855 | NS375_00415 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.548 |
| KTR99302.1 | dnaQ | NS375_09855 | NS375_08055 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.423 |
| KTR99302.1 | secB | NS375_09855 | NS375_17790 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.453 |
| KTR99302.1 | smpB | NS375_09855 | NS375_09850 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.610 |
| KTR99302.1 | sspA | NS375_09855 | NS375_19520 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Stringent starvation protein A; Transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily. | 0.581 |
| KTR99302.1 | ubiA | NS375_09855 | NS375_03735 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.600 |
| KTR99302.1 | ubiB | NS375_09855 | NS375_08715 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.492 |
| KTR99302.1 | ubiF | NS375_09855 | NS375_06650 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.442 |
| KTR99302.1 | ubiG | NS375_09855 | NS375_11465 | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.646 |
| KTR99303.1 | KTR99302.1 | NS375_09860 | NS375_09855 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family. | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
| KTR99303.1 | smpB | NS375_09860 | NS375_09850 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.575 |
| KTR99303.1 | sspA | NS375_09860 | NS375_19520 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0125 (RnfH) family. | Stringent starvation protein A; Transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily. | 0.501 |
| KTS01597.1 | KTR99302.1 | NS375_00415 | NS375_09855 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.548 |
| KTS01597.1 | sspA | NS375_00415 | NS375_19520 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Stringent starvation protein A; Transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily. | 0.449 |
| KTS01597.1 | ubiA | NS375_00415 | NS375_03735 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.760 |
| KTS01597.1 | ubiB | NS375_00415 | NS375_08715 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.619 |
| KTS01597.1 | ubiG | NS375_00415 | NS375_11465 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.775 |
| dnaQ | KTR99302.1 | NS375_08055 | NS375_09855 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.423 |
| dnaQ | secB | NS375_08055 | NS375_17790 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.487 |