STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHD19927.1TIGRFAM: Malate synthase A; KEGG: pct:PC1_3779 malate synthase; PFAM: Malate synthase-like, core; Belongs to the malate synthase family. (532 aa)    
Predicted Functional Partners:
EHD19928.1
TIGRFAM: Isocitrate lyase; KEGG: pct:PC1_3778 isocitrate lyase; PFAM: Isocitrate lyase/phosphorylmutase.
 
 0.999
EHD23029.1
PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Phosphate acetyl/butaryl transferase; KEGG: pct:PC1_0754 malic enzyme.
  
 
 0.957
EHD20765.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.947
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.938
EHD21083.1
D-lactate dehydrogenase (cytochrome); KEGG: pwa:Pecwa_2755 FAD linked oxidase domain protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal.
  
 
 0.922
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 0.911
EHD19821.1
KEGG: pct:PC1_3911 citrate synthase I; TIGRFAM: Citrate synthase, type II; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
   
 0.899
EHD22480.1
KEGG: eca:ECA1356 type II citrate synthase; TIGRFAM: Citrate synthase, type II; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
   
 0.899
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
 
  
 0.863
EHD19681.1
Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
   
 
 0.862
Your Current Organism:
Brenneria sp. EniD312
NCBI taxonomy Id: 598467
Other names: B. sp. EniD312
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.