STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHD19973.1KEGG: enc:ECL_03983 HlyD family type I secretion membrane fusion protein; TIGRFAM: Type I secretion membrane fusion protein, HlyD; PFAM: Secretion protein HlyD. (394 aa)    
Predicted Functional Partners:
EHD19972.1
SMART: ATPase, AAA+ type, core; TIGRFAM: ATPase, type I secretion system; KEGG: enc:ECL_03982 type I secretion system ATPase family protein; PFAM: ABC transporter-like; ABC transporter, transmembrane region.
 0.997
EHD19971.1
KEGG: TolC family type I secretion outer membrane protein; TIGRFAM: Type I secretion outer membrane protein, TolC; PFAM: Outer membrane efflux protein.
 0.987
EHD20540.1
SMART: ATPase, AAA+ type, core; TIGRFAM: ATPase, type I secretion system; KEGG: eca:ECA3268 putative toxin secretion ATP-binding protein; PFAM: ABC transporter-like.
 0.985
EHD20355.1
Phosphonate-transporting ATPase; PFAM: ABC transporter-like; Protein of unknown function DUF214, permase predicted; KEGG: hse:Hsero_2045 antimicrobial peptide ABC transporter ATPase; SMART: ATPase, AAA+ type, core; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
 
 0.958
macB
Phosphonate-transporting ATPase; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.958
EHD20541.1
KEGG: pct:PC1_3061 type I secretion outer membrane protein, TolC family; TIGRFAM: Type I secretion outer membrane protein, TolC; PFAM: Outer membrane efflux protein.
 
 0.940
EHD23418.1
KEGG: pct:PC1_0313 outer membrane channel protein; TIGRFAM: Type I secretion outer membrane protein, TolC; PFAM: Outer membrane efflux protein.
  
 0.906
EHD20547.1
Type 1 secretion target domain; KEGG: pct:PC1_3060 von Willebrand factor type A; TIGRFAM: Type 1 secretion, target domain, C-terminal; PFAM: von Willebrand factor, type A; Haemolysin-type calcium-binding region.
 
 
 0.782
EHD19970.1
TIGRFAM: Type 1 secretion, target domain, C-terminal; VCBS repeat domain; KEGG: cro:ROD_25701 large repetitive protein.
 
     0.765
EHD20550.1
PFAM: Transglutaminase-like cysteine peptidase, predicted; KEGG: pwa:Pecwa_1218 transglutaminase family protein cysteine peptidase BTLCP.
 
  
 0.752
Your Current Organism:
Brenneria sp. EniD312
NCBI taxonomy Id: 598467
Other names: B. sp. EniD312
Server load: low (22%) [HD]
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