node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHD19681.1 | EHD22990.1 | BrE312_0224 | BrE312_3640 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | TIGRFAM: Tartrate dehydrogenase; KEGG: dda:Dd703_3166 tartrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | 0.467 |
EHD19681.1 | EHD23045.1 | BrE312_0224 | BrE312_3695 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: pct:PC1_0698 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | 0.929 |
EHD19681.1 | fadJ | BrE312_0224 | BrE312_1311 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.965 |
EHD19681.1 | ilvD | BrE312_0224 | BrE312_0235 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: pwa:Pecwa_4218 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.816 |
EHD19681.1 | leuA | BrE312_0224 | BrE312_0673 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.896 |
EHD19681.1 | leuB | BrE312_0224 | BrE312_0672 | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.467 |
EHD20120.1 | EHD22990.1 | BrE312_0676 | BrE312_3640 | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | TIGRFAM: Tartrate dehydrogenase; KEGG: dda:Dd703_3166 tartrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | 0.936 |
EHD20120.1 | EHD23045.1 | BrE312_0676 | BrE312_3695 | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: pct:PC1_0698 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | 0.883 |
EHD20120.1 | ilvD | BrE312_0676 | BrE312_0235 | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: pwa:Pecwa_4218 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.878 |
EHD20120.1 | ilvE | BrE312_0676 | BrE312_0234 | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.628 |
EHD20120.1 | leuA | BrE312_0676 | BrE312_0673 | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.884 |
EHD20120.1 | leuB | BrE312_0676 | BrE312_0672 | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.951 |
EHD20120.1 | leuC | BrE312_0676 | BrE312_0671 | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.785 |
EHD20120.1 | leuD | BrE312_0676 | BrE312_0670 | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.900 |
EHD22990.1 | EHD19681.1 | BrE312_3640 | BrE312_0224 | TIGRFAM: Tartrate dehydrogenase; KEGG: dda:Dd703_3166 tartrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.467 |
EHD22990.1 | EHD20120.1 | BrE312_3640 | BrE312_0676 | TIGRFAM: Tartrate dehydrogenase; KEGG: dda:Dd703_3166 tartrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | TIGRFAM: Acetolactate synthase, small subunit; KEGG: pct:PC1_3604 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT. | 0.936 |
EHD22990.1 | EHD23045.1 | BrE312_3640 | BrE312_3695 | TIGRFAM: Tartrate dehydrogenase; KEGG: dda:Dd703_3166 tartrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | TIGRFAM: Pyruvate-flavodoxin oxidoreductase; KEGG: pct:PC1_0698 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding. | 0.887 |
EHD22990.1 | fadJ | BrE312_3640 | BrE312_1311 | TIGRFAM: Tartrate dehydrogenase; KEGG: dda:Dd703_3166 tartrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.467 |
EHD22990.1 | ilvD | BrE312_3640 | BrE312_0235 | TIGRFAM: Tartrate dehydrogenase; KEGG: dda:Dd703_3166 tartrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: pwa:Pecwa_4218 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.762 |
EHD22990.1 | leuA | BrE312_3640 | BrE312_0673 | TIGRFAM: Tartrate dehydrogenase; KEGG: dda:Dd703_3166 tartrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.890 |