STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHD20454.1KEGG: pct:PC1_3149 putative two-component response-regulatory protein YehT; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region. (238 aa)    
Predicted Functional Partners:
EHD19767.1
KEGG: pwa:Pecwa_4137 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; GAF; ATP-binding region, ATPase-like; SMART: GAF.
 
 0.963
EHD21696.1
KEGG: pct:PC1_1878 signal transduction histidine kinase, LytS; PFAM: Signal transduction histidine kinase, internal region; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; GAF; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like.
 
 0.962
EHD23429.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: pwa:Pecwa_0307 aerobic respiration control sensor protein ArcB; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; Signal transduction response regulator, receiver region; Signal transduction [...]
  
 
 0.843
rcsC
Integral membrane sensor hybrid histidine kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
  
 
 0.753
EHD19516.1
Signal transduction histidine kinase regulating citrate/malate metabolism; KEGG: pwa:Pecwa_0044 sensory histidine kinase DcuS; PFAM: ATP-binding region, ATPase-like; PAS fold; SMART: ATP-binding region, ATPase-like.
 
  
 0.688
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.601
EHD19517.1
Response regulator receiver and unknown domain protein; KEGG: pct:PC1_0039 DNA-binding transcriptional activator DcuR; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
  
  
 0.600
EHD20456.1
TIGRFAM: Chorismate mutase, T-protein; KEGG: pwa:Pecwa_1132 bifunctional chorismate mutase/prephenate dehydrogenase; PFAM: Chorismate mutase, type II; Prephenate dehydrogenase.
       0.598
EHD20455.1
Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
       0.486
EHD21695.1
KEGG: eca:ECA2431 two-component response regulator; PFAM: LytTr DNA-binding region; Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
  
  
 
0.479
Your Current Organism:
Brenneria sp. EniD312
NCBI taxonomy Id: 598467
Other names: B. sp. EniD312
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.