| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHD23431.1 | EHD23843.1 | BrE312_4110 | BrE312_4530 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.999 |
| EHD23431.1 | aspS | BrE312_4110 | BrE312_2463 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.854 |
| EHD23431.1 | gmk | BrE312_4110 | BrE312_4398 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.536 |
| EHD23431.1 | gpt | BrE312_4110 | BrE312_0936 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.435 |
| EHD23431.1 | guaA | BrE312_4110 | BrE312_1173 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.981 |
| EHD23431.1 | guaB | BrE312_4110 | BrE312_1172 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.771 |
| EHD23431.1 | guaC | BrE312_4110 | BrE312_0705 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.771 |
| EHD23431.1 | purL | BrE312_4110 | BrE312_1129 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.965 |
| EHD23431.1 | pyrG | BrE312_4110 | BrE312_0858 | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.964 |
| EHD23843.1 | EHD23431.1 | BrE312_4530 | BrE312_4110 | TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | KEGG: pct:PC1_0299 glutamate synthase subunit alpha; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal. | 0.999 |
| EHD23843.1 | aspS | BrE312_4530 | BrE312_2463 | TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.511 |
| EHD23843.1 | guaA | BrE312_4530 | BrE312_1173 | TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.982 |
| EHD23843.1 | guaB | BrE312_4530 | BrE312_1172 | TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.477 |
| EHD23843.1 | guaC | BrE312_4530 | BrE312_0705 | TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.477 |
| EHD23843.1 | purL | BrE312_4530 | BrE312_1129 | TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.931 |
| EHD23843.1 | pyrG | BrE312_4530 | BrE312_0858 | TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.760 |
| argS | aspS | BrE312_2472 | BrE312_2463 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: pct:PC1_1807 arginyl-tRNA synthetase. | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.848 |
| argS | gmk | BrE312_2472 | BrE312_4398 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: pct:PC1_1807 arginyl-tRNA synthetase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.456 |
| argS | guaA | BrE312_2472 | BrE312_1173 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: pct:PC1_1807 arginyl-tRNA synthetase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.967 |
| argS | guaC | BrE312_2472 | BrE312_0705 | TIGRFAM: Arginyl-tRNA synthetase, class Ic; HAMAP: Arginyl-tRNA synthetase, class Ic; KEGG: pct:PC1_1807 arginyl-tRNA synthetase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.450 |
