STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (349 aa)    
Predicted Functional Partners:
pyrB
PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase; KEGG: pwa:Pecwa_0420 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.950
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.946
carB
TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: pwa:Pecwa_3840 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Belongs to the CarB family.
   
 
 0.920
EHD23843.1
TIGRFAM: Putative selenate reductase YgfK; KEGG: eic:NT01EI_3524 putative selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.862
pyrI
Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
   
 
  0.861
EHD19541.1
TIGRFAM: Dihydroorotate dehydrogenase, class 1, core; KEGG: dda:Dd703_0045 dihydropyrimidine dehydrogenase; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
  
 
 0.850
EHD19679.1
KEGG: pct:PC1_4046 FMN reductase; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase FAD-binding region.
    
  0.727
carA
TIGRFAM: Carbamoyl phosphate synthase, small subunit; KEGG: pct:PC1_3648 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family.
  
  
 0.717
EHD19542.1
Dihydropyrimidinase; TIGRFAM: D-hydantoinase; KEGG: dda:Dd703_0046 phenylhydantoinase; PFAM: Amidohydrolase 1.
    
 0.656
EHD23841.1
Dihydropyrimidinase; TIGRFAM: D-hydantoinase; KEGG: aha:AHA_2164 phenylhydantoinase; PFAM: Amidohydrolase 1.
    
 0.656
Your Current Organism:
Brenneria sp. EniD312
NCBI taxonomy Id: 598467
Other names: B. sp. EniD312
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