| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EHD19746.1 | EHD22771.1 | BrE312_0292 | BrE312_3406 | TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: pwa:Pecwa_4154 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | 0.836 |
| EHD19746.1 | EHD23369.1 | BrE312_0292 | BrE312_4043 | TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: pwa:Pecwa_4154 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. | DEAD/DEAH box helicase domain protein; KEGG: eoh:ECO103_5067 putative helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | 0.779 |
| EHD19746.1 | mfd | BrE312_0292 | BrE312_1651 | TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: pwa:Pecwa_4154 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.645 |
| EHD19746.1 | polA | BrE312_0292 | BrE312_4417 | TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: pwa:Pecwa_4154 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.937 |
| EHD19746.1 | recA | BrE312_0292 | BrE312_1008 | TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: pwa:Pecwa_4154 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.863 |
| EHD19746.1 | sbcD | BrE312_0292 | BrE312_3405 | TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: pwa:Pecwa_4154 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.865 |
| EHD22771.1 | EHD19746.1 | BrE312_3406 | BrE312_0292 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: pwa:Pecwa_4154 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. | 0.836 |
| EHD22771.1 | EHD23369.1 | BrE312_3406 | BrE312_4043 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | DEAD/DEAH box helicase domain protein; KEGG: eoh:ECO103_5067 putative helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | 0.835 |
| EHD22771.1 | frr | BrE312_3406 | BrE312_3490 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.836 |
| EHD22771.1 | mfd | BrE312_3406 | BrE312_1651 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.848 |
| EHD22771.1 | polA | BrE312_3406 | BrE312_4417 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.922 |
| EHD22771.1 | recA | BrE312_3406 | BrE312_1008 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.865 |
| EHD22771.1 | sbcD | BrE312_3406 | BrE312_3405 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.999 |
| EHD22771.1 | uvrA | BrE312_3406 | BrE312_0748 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.896 |
| EHD22771.1 | uvrB | BrE312_3406 | BrE312_1501 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] | 0.883 |
| EHD22771.1 | uvrC | BrE312_3406 | BrE312_2733 | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.894 |
| EHD23369.1 | EHD19746.1 | BrE312_4043 | BrE312_0292 | DEAD/DEAH box helicase domain protein; KEGG: eoh:ECO103_5067 putative helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type, N-terminal; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; KEGG: pwa:Pecwa_4154 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain. | 0.779 |
| EHD23369.1 | EHD22771.1 | BrE312_4043 | BrE312_3406 | DEAD/DEAH box helicase domain protein; KEGG: eoh:ECO103_5067 putative helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | PFAM: RecF/RecN/SMC protein, N-terminal; KEGG: pwa:Pecwa_3304 exonuclease SbcC. | 0.835 |
| EHD23369.1 | mfd | BrE312_4043 | BrE312_1651 | DEAD/DEAH box helicase domain protein; KEGG: eoh:ECO103_5067 putative helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.645 |
| EHD23369.1 | polA | BrE312_4043 | BrE312_4417 | DEAD/DEAH box helicase domain protein; KEGG: eoh:ECO103_5067 putative helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.937 |
