STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHD23002.1DNA-3-methyladenine glycosylase II; PFAM: HhH-GPD domain; KEGG: pct:PC1_0790 DNA-3-methyladenine glycosylase II; SMART: HhH-GPD domain. (243 aa)    
Predicted Functional Partners:
EHD23001.1
Ada DNA repair protein and transcriptional regulator, AraC family; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; Ada DNA repair, metal-binding; Helix-turn-helix, AraC type; Methylguanine DNA methyltransferase, ribonuclease-like; KEGG: pwa:Pecwa_1027 transcriptional regulator, AraC family; SMART: Helix-turn-helix, AraC domain.
 
 
 0.965
EHD21590.1
Exodeoxyribonuclease III; TIGRFAM: AP endonuclease, family 1; Exodeoxyribonuclease III xth; KEGG: pwa:Pecwa_2270 exonuclease III; PFAM: Endonuclease/exonuclease/phosphatase.
  
 0.921
EHD23000.1
2OG-Fe(II) oxygenase; PFAM: Oxoglutarate/iron-dependent oxygenase; KEGG: pwa:Pecwa_1028 2OG-Fe(II) oxygenase.
     
 0.731
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.665
EHD22680.1
KEGG: pwa:Pecwa_3228 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; Belongs to the 5'-nucleotidase family.
   
 
  0.648
EHD22487.1
PFAM: Protein of unknown function DUF523; KEGG: dda:Dd703_1133 protein of unknown function DUF1722.
   
 
  0.638
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
 
 0.586
nfo
Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
    
 
 0.579
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 
 0.578
mutS
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
   
 
 0.499
Your Current Organism:
Brenneria sp. EniD312
NCBI taxonomy Id: 598467
Other names: B. sp. EniD312
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.