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glyA protein (Nautilia profundicola) - STRING interaction network
"glyA" - Serine hydroxymethyltransferase in Nautilia profundicola
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (415 aa)    
Predicted Functional Partners:
purH
Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355 (504 aa)
   
  0.993
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (284 aa)
   
 
  0.990
NAMH_0284
Phosphoribosylglycinamide formyltransferase; Identified by match to protein family HMM PF00551 (171 aa)
 
 
  0.963
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus (294 aa)
     
 
  0.952
lysS
Lysine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family (502 aa)
   
   
  0.949
rpiB
Ribose 5-phosphate isomerase B; Identified by match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120 (142 aa)
   
 
  0.944
NAMH_1486
Folylpolyglutamate synthetase; Identified by match to protein family HMM PF08245; match to protein family HMM TIGR01499 (394 aa)
   
  0.939
NAMH_0769
Glucose inhibited division protein A; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family (430 aa)
 
 
  0.938
serB
Phosphoserine phosphatase SerB; Identified by match to protein family HMM PF00702; match to protein family HMM PF06888; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488 (206 aa)
   
  0.931
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family (235 aa)
   
 
  0.928
Your Current Organism:
Nautilia profundicola
NCBI taxonomy Id: 598659
Other names: N. profundicola AmH, Nautilia profundicola, Nautilia profundicola AmH, Nautilia profundicola str. AmH, Nautilia profundicola strain AmH, Nautilia sp. AmH, epsilon proteobacterium AmH
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