STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
U3JE12_FICALUncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (608 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.975
ITSN2
Intersectin 2.
    
 
 0.914
ITSN1
Intersectin 1.
    
 
 0.784
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 0.783
CLTC
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.732
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.695
PINK1
PTEN induced kinase 1.
    
 0.653
WASL
WASP like actin nucleation promoting factor.
     
 0.640
SH3GL1
SH3 domain containing GRB2 like 1, endophilin A2.
   
 0.629
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1.
   
 0.629
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.