STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERBB4Receptor protein-tyrosine kinase. (1228 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.988
SHC1
SHC adaptor protein 1.
    
 0.973
NRG1
Neuregulin 1.
    
 0.973
NRG2
Neuregulin 2.
    
 0.973
SHC3
SHC adaptor protein 3.
    
 0.973
HBEGF
Heparin binding EGF like growth factor.
    
 0.971
SHC4
SHC adaptor protein 4.
    
 0.964
SHC2
Uncharacterized protein.
    
 0.964
EREG
Epiregulin.
    
 0.963
PLCG1
Phosphoinositide phospholipase C.
    
 0.957
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.