STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (366 aa)    
Predicted Functional Partners:
CXCL12
C-X-C motif chemokine ligand 12.
   
 0.992
U3KIW0_FICAL
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
 
0.970
LOC101819083
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
 
0.966
GNA12
G protein subunit alpha 12.
    
 0.936
GNA13
G protein subunit alpha 13.
    
 0.924
ACKR3
Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
0.887
CXCL8-2
Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.
   
 
 0.838
CCR7
C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.
   
 
0.792
CXCR5
C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.
    
0.777
ARRB1
Arrestin beta 1.
   
 0.773
Your Current Organism:
Ficedula albicollis
NCBI taxonomy Id: 59894
Other names: F. albicollis, collared flycatcher
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.