STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccrd_008351HECT domain-containing protein. (990 aa)    
Predicted Functional Partners:
Ccrd_021772
HECT-like protein.
   
 
0.871
Ccrd_021771
Armadillo-like helical.
   
 
 0.871
Ccrd_001397
Armadillo.
   
 
0.869
Ccrd_017610
Armadillo.
   
 
0.869
Ccrd_009434
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.834
Ccrd_024380
26S proteasome non-ATPase regulatory subunit 2 homolog; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
    
 
 0.718
Ccrd_003819
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
      
 0.717
Ccrd_019225
Uncharacterized protein.
      
 0.710
Ccrd_012656
Aminoacyl-tRNA synthetase, class II.
      
 0.664
Ccrd_017922
Uncharacterized protein.
      
 0.663
Your Current Organism:
Cynara cardunculus
NCBI taxonomy Id: 59895
Other names: C. cardunculus var. scolymus, Cynara cardunculus Scolymus Group, Cynara cardunculus subsp. scolymus, Cynara cardunculus subsp. scolymus (L.) Hayek, Cynara cardunculus var. scolymus, Cynara cardunculus var. scolymus (L.) Fiori, Cynara scolymus, Cynara scolymus L., artichoke, globe artichoke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.