STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccrd_013806DNA polymerase alpha/epsilon, subunit B. (465 aa)    
Predicted Functional Partners:
Ccrd_004748
DNA helicase; Belongs to the MCM family.
   
 0.999
Ccrd_026601
Histone-fold.
    
 0.998
Ccrd_026272
DNA helicase.
   
 0.998
Ccrd_025941
DNA helicase; Belongs to the MCM family.
   
 0.998
Ccrd_015181
WD_REPEATS_REGION domain-containing protein.
   
 
 0.998
Ccrd_012577
DNA polymerase.
   
 0.997
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.996
Ccrd_002141
CDC45 family.
   
 0.995
Ccrd_009292
CDC45 family.
   
 0.995
Ccrd_017309
GINS complex.
   
 
 0.991
Your Current Organism:
Cynara cardunculus
NCBI taxonomy Id: 59895
Other names: C. cardunculus var. scolymus, Cynara cardunculus Scolymus Group, Cynara cardunculus subsp. scolymus, Cynara cardunculus subsp. scolymus (L.) Hayek, Cynara cardunculus var. scolymus, Cynara cardunculus var. scolymus (L.) Fiori, Cynara scolymus, Cynara scolymus L., artichoke, globe artichoke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.