STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccrd_010804D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (596 aa)    
Predicted Functional Partners:
Ccrd_012454
Aminotransferase, class V/Cysteine desulfurase.
  
 0.993
Ccrd_005083
Pyridoxal phosphate-dependent transferase, major region, subdomain 2.
  
 0.936
Ccrd_016610
Aminotransferase, class V/Cysteine desulfurase.
  
 0.936
Ccrd_005730
Histidine phosphatase superfamily, clade-1.
    
 0.919
Ccrd_022216
Histidine phosphatase superfamily, clade-1.
    
 0.919
Ccrd_002926
Alkaline phosphatase-like, alpha/beta/alpha.
    
 0.918
Ccrd_004734
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 0.901
Ccrd_019720
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
 0.901
Ccrd_004642
ACT domain-containing protein.
  
  
 
0.900
Ccrd_008294
Aminotransferase, class V/Cysteine desulfurase.
  
 
 0.880
Your Current Organism:
Cynara cardunculus
NCBI taxonomy Id: 59895
Other names: C. cardunculus var. scolymus, Cynara cardunculus Scolymus Group, Cynara cardunculus subsp. scolymus, Cynara cardunculus subsp. scolymus (L.) Hayek, Cynara cardunculus var. scolymus, Cynara cardunculus var. scolymus (L.) Fiori, Cynara scolymus, Cynara scolymus L., artichoke, globe artichoke
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