node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccrd_004734 | Ccrd_006555 | A0A118JVF4 | A0A103XIK5 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.972 |
Ccrd_004734 | Ccrd_010033 | A0A118JVF4 | A0A118K732 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | FAD dependent oxidoreductase. | 0.972 |
Ccrd_004734 | Ccrd_011693 | A0A118JVF4 | A0A103YIT7 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.790 |
Ccrd_004734 | Ccrd_012177 | A0A118JVF4 | A0A118K5Q5 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Formate-tetrahydrofolate ligase, FTHFS. | 0.912 |
Ccrd_004734 | Ccrd_012245 | A0A118JVF4 | A0A124SHF4 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.972 |
Ccrd_004734 | Ccrd_015191 | A0A118JVF4 | A0A103YCB6 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | HAD-like domain-containing protein. | 0.757 |
Ccrd_004734 | Ccrd_015735 | A0A118JVF4 | A0A124SGC3 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | AICARFT/IMPCHase bienzyme. | 0.772 |
Ccrd_004734 | Ccrd_018555 | A0A118JVF4 | A0A118K1N4 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Urease accessory protein UreD. | 0.771 |
Ccrd_004734 | Ccrd_019231 | A0A118JVF4 | A0A118K185 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.970 |
Ccrd_004734 | Ccrd_019720 | A0A118JVF4 | A0A124SF37 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.999 |
Ccrd_006555 | Ccrd_004734 | A0A103XIK5 | A0A118JVF4 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.972 |
Ccrd_006555 | Ccrd_010033 | A0A103XIK5 | A0A118K732 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | FAD dependent oxidoreductase. | 0.985 |
Ccrd_006555 | Ccrd_011693 | A0A103XIK5 | A0A103YIT7 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.717 |
Ccrd_006555 | Ccrd_012177 | A0A103XIK5 | A0A118K5Q5 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Formate-tetrahydrofolate ligase, FTHFS. | 0.919 |
Ccrd_006555 | Ccrd_012245 | A0A103XIK5 | A0A124SHF4 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.999 |
Ccrd_006555 | Ccrd_015191 | A0A103XIK5 | A0A103YCB6 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | HAD-like domain-containing protein. | 0.700 |
Ccrd_006555 | Ccrd_015735 | A0A103XIK5 | A0A124SGC3 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | AICARFT/IMPCHase bienzyme. | 0.840 |
Ccrd_006555 | Ccrd_018555 | A0A103XIK5 | A0A118K1N4 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Urease accessory protein UreD. | 0.840 |
Ccrd_006555 | Ccrd_019231 | A0A103XIK5 | A0A118K185 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.924 |
Ccrd_006555 | Ccrd_019720 | A0A103XIK5 | A0A124SF37 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.972 |