STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccrd_002423Adenine phosphoribosyl transferase. (215 aa)    
Predicted Functional Partners:
Ccrd_000984
Adenosine/AMP deaminase domain-containing protein.
   
 0.853
Ccrd_007896
Asparagine synthase.
  
 
 0.835
Ccrd_003193
Guanylate kinase.
  
 
 0.799
Ccrd_016656
Guanylate kinase.
  
 
 0.799
Ccrd_009496
Galactose oxidase/kelch, beta-propeller.
  
 
 0.799
Ccrd_004734
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.750
Ccrd_019720
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.750
Ccrd_021440
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 0.745
Ccrd_011693
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.736
Ccrd_024486
Adenosine/AMP deaminase active site-containing protein.
   
 0.726
Your Current Organism:
Cynara cardunculus
NCBI taxonomy Id: 59895
Other names: C. cardunculus var. scolymus, Cynara cardunculus Scolymus Group, Cynara cardunculus subsp. scolymus, Cynara cardunculus subsp. scolymus (L.) Hayek, Cynara cardunculus var. scolymus, Cynara cardunculus var. scolymus (L.) Fiori, Cynara scolymus, Cynara scolymus L., artichoke, globe artichoke
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