STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHSSSoluble hydrogenase small subunit; BELONGS TO CLASS-V OF PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES; Alternative locus ID: PMED4_00341. (384 aa)    
Predicted Functional Partners:
cbiD
CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
       0.664
serA
Putative D-3-phosphoglycerate dehydrogenase (PGDH); Alternative locus ID: PMED4_15221; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.628
cobC
Possible alpha-ribazole-5'-P phosphatase; Phosphatase involved in the assembly of the nucleotide loop of cobalamin; Citation: O'Toole et al. (1994) J. Biol. Chem. 269:26503-26511; Alternative locus ID: PMED4_05641; Belongs to the phosphoglycerate mutase family.
 
 
  0.577
guaA
Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.575
glsF,
Ferredoxin-dependent glutamate synthase, Fd-GOGAT; Alternative locus ID: PMED4_17221.
  
  
 0.553
purD
Phosphoribosylglycinamide synthetase; Alternative locus ID: PMED4_15081; Belongs to the GARS family.
  
    0.480
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
  
 0.471
guaB
Putative IMP dehydrogenase; Alternative locus ID: PMED4_12081.
   
 0.417
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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