| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PMM0101 | rimO | PMM0101 | PMM0102 | Conserved hypothetical protein; Alternative locus ID: PMED4_01061. | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.633 |
| PMM1101 | polA | PMM1101 | PMM1140 | Putative ATP-dependent RNA helicase; Alternative locus ID: PMED4_12471; Belongs to the DEAD box helicase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.422 |
| PMM1101 | rimO | PMM1101 | PMM0102 | Putative ATP-dependent RNA helicase; Alternative locus ID: PMED4_12471; Belongs to the DEAD box helicase family. | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.503 |
| PMM1101 | rps17, | PMM1101 | PMM1549 | Putative ATP-dependent RNA helicase; Alternative locus ID: PMED4_12471; Belongs to the DEAD box helicase family. | 30S Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.510 |
| era | lepB | PMM1281 | PMM0513 | GTP-binding protein ERA homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Signal peptidase I; Alternative locus ID: PMED4_05621; Belongs to the peptidase S26 family. | 0.420 |
| era | rimO | PMM1281 | PMM0102 | GTP-binding protein ERA homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.526 |
| era | rlmN | PMM1281 | PMM1481 | GTP-binding protein ERA homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.435 |
| era | rps17, | PMM1281 | PMM1549 | GTP-binding protein ERA homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.429 |
| lepB | era | PMM0513 | PMM1281 | Signal peptidase I; Alternative locus ID: PMED4_05621; Belongs to the peptidase S26 family. | GTP-binding protein ERA homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.420 |
| lepB | recA | PMM0513 | PMM1562 | Signal peptidase I; Alternative locus ID: PMED4_05621; Belongs to the peptidase S26 family. | RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.538 |
| lepB | rimO | PMM0513 | PMM0102 | Signal peptidase I; Alternative locus ID: PMED4_05621; Belongs to the peptidase S26 family. | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.642 |
| nadB | rimO | PMM0100 | PMM0102 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.764 |
| polA | PMM1101 | PMM1140 | PMM1101 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Putative ATP-dependent RNA helicase; Alternative locus ID: PMED4_12471; Belongs to the DEAD box helicase family. | 0.422 |
| polA | recA | PMM1140 | PMM1562 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.973 |
| polA | rimO | PMM1140 | PMM0102 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.479 |
| recA | lepB | PMM1562 | PMM0513 | RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Signal peptidase I; Alternative locus ID: PMED4_05621; Belongs to the peptidase S26 family. | 0.538 |
| recA | polA | PMM1562 | PMM1140 | RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.973 |
| recA | rimO | PMM1562 | PMM0102 | RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.577 |
| rimO | PMM0101 | PMM0102 | PMM0101 | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | Conserved hypothetical protein; Alternative locus ID: PMED4_01061. | 0.633 |
| rimO | PMM1101 | PMM0102 | PMM1101 | Possible Fe-S oxidoreductase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | Putative ATP-dependent RNA helicase; Alternative locus ID: PMED4_12471; Belongs to the DEAD box helicase family. | 0.503 |