Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadCNicotinate-nucleotide pyrophosphorylase:Quinolinate phosphoriobsyl transferase; Alternative locus ID: PMED4_01941; Belongs to the NadC/ModD family. (288 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase A protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.999
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.996
PMM1445
Putative nicotinate-nucleotide adenylyltransferase; Alternative locus ID: PMED4_16541; Belongs to the NadD family.
    
 0.927
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.901
hisC
Aminotransferases class-I; Conserved hypothetical assignment; Alternative locus ID: PMED4_01921.
       0.750
argS
Arginyl-tRNA synthetase; Alternative locus ID: PMED4_01931.
       0.750
panB
Putative Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
      0.666
mnmE
Putative thiophen / furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
    0.650
nadE
Carbon-nitrogen hydrolase:NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.648
PMM0257
Molybdenum cofactor biosynthesis protein; Alternative locus ID: PMED4_02621; Belongs to the CinA family.
     
 0.634
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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