Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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spoTGuanosine-3',5'-bis(diphosphate) 3'-diphosphatase, (ppGpp)ase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (769 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.937
ppx
Putative exopolyphosphatase; Alternative locus ID: PMED4_05051.
   
 
 0.926
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.911
PMM0155
Conserved hypothetical protein; Alternative locus ID: PMED4_01611.
   
 
  0.900
nrdJ
Ribonucleotide reductase (Class II); Citation: Gleason and Olszewski (2002) J. Bacteriol. 184:6544-6550; Alternative locus ID: PMED4_07171.
     
  0.900
rps6,
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 
 
 0.877
rpl9,
50S ribosomal protein L9; Binds to the 23S rRNA.
  
 
   0.876
rps12,
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
    
 
 0.872
rpl13,
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.872
rpl11,
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
 
 0.866
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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