Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgk,Phosphoglycerate kinase; Alternative locus ID: PMED4_02011; Belongs to the phosphoglycerate kinase family. (402 aa)    
Predicted Functional Partners:
tpi,
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
gap2
Glyceraldehyde 3-phosphate dehydrogenase(NADP+)(phosphorylating); Citation: AJ245541; Mol Biol Evol 2001 Dec;18(12):2240-2249; Alternative locus ID: PMED4_00221; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.998
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.990
gap1
Putative glyceraldehyde 3-phosphate dehydrogenase; Alternative locus ID: PMED4_07871; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.976
pgmI
Phosphoglycerate mutase, co-factor-independent (iPGM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.972
pykF
Pyruvate kinase; Alternative locus ID: PMED4_10231; Belongs to the pyruvate kinase family.
 
 
 0.964
CbbA
Fructose-bisphosphate/sedoheptulose-1, 7-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.944
pgi
Phosphoglucose isomerase (PGI); Alternative locus ID: PMED4_10011.
  
 
 0.930
rbcL,
Ribulose bisphosphate carboxylase, large chain; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily.
    
 0.929
rbcS,
Ribulose bisphosphate carboxylase, small chain; Alternative locus ID: PMED4_06001.
    
 0.926
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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