STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (389 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.990
PMM0514
Putative dihydroorotase; Alternative locus ID: PMED4_05631.
  
 0.990
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
 
 
 0.985
pheT
Phenylalanyl-tRNA synthetase beta chain; Putative assignment; Alternative locus ID: PMED4_09811; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.959
pyrB
Aspartate carbamoyltransferase; Putative assignment; Alternative locus ID: PMED4_02381; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.940
carB
Carbamoyl-phosphate synthase, large subunit; Alternative locus ID: PMED4_09191; Belongs to the CarB family.
 
 
 0.928
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
  
 0.919
carA,
STAS domain:Anti-sigma factor antagonist; Alternative locus ID: PMED4_10606; Belongs to the CarA family.
 
  
 0.913
hisC/cobC
Aminotransferases class-I; Citation: Crouzet et al. (1990) J. Bacteriol. 172:5968-5979; Alternative locus ID: PMED4_02041.
  
  
 0.822
rnhA
Possible ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.810
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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