Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PMM0222Putative assignment; Alternative locus ID: PMED4_02271; Belongs to the AspA/AstE family. Aspartoacylase subfamily. (295 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
  0.900
pyrB
Aspartate carbamoyltransferase; Putative assignment; Alternative locus ID: PMED4_02381; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.900
purA,adeK
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
  0.900
aspC
Aminotransferases class-I; Possible role in phosphonate metabolism; Alternative locus ID: PMED4_07301.
     
  0.900
PMM0821
Conserved hypothetical protein; Alternative locus ID: PMED4_09151.
     
  0.900
argG
Argininosuccinate synthase; Alternative locus ID: PMED4_19181; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
  0.900
lysC
Aspartate kinase; Putative assignment; alpha and beta subunits, and additional region with similarity to beta subunit (BY SIMILARITY); Alternative locus ID: PMED4_18581.
    
  0.807
purQ
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
     
  0.800
glnA
Glutamine synthetase, glutamate--ammonia ligase; Alternative locus ID: PMED4_10311.
     
  0.800
ho1
Heme oxygenase; Alternative locus ID: PMED4_18041.
  
     0.747
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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