STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
dfpPutative p-pantothenate cysteine ligase and p-pantothenenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (418 aa)    
Predicted Functional Partners:
coaD
Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
 
 0.939
PMM0080
Conserved hypothetical protein; Alternative locus ID: PMED4_00831.
  
 
 0.927
panC,
Putative bifunctional enzyme; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
 
 
 0.907
aspC
Aminotransferases class-I; Possible role in phosphonate metabolism; Alternative locus ID: PMED4_07301.
  
  0.837
cysK2
O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_01291; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
  0.808
cysK1
O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_04501; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.807
PMM0230
Conserved hypothetical protein; Alternative locus ID: PMED4_02351.
       0.773
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 0.689
PMM0231
Conserved hypothetical protein; Alternative locus ID: PMED4_02361.
       0.611
PMM0232
Conserved hypothetical protein; Alternative locus ID: PMED4_02371.
  
    0.572
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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