node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CobN | CobS | PMM0879 | PMM0270 | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.789 |
CobN | PMM0245 | PMM0879 | PMM0245 | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | cob(I)alamin adenosyltransferase; Alternative locus ID: PMED4_02501. | 0.904 |
CobN | PMM1570 | PMM0879 | PMM1570 | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Alternative locus ID: PMED4_17801. | 0.904 |
CobN | cbiA,cobB | PMM0879 | PMM1072 | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | Putative Cobyrinic acid a,c-diamide synthase; BELONGS TO THE SIRTUIN FAMILY; Citation: Tsang and Escalante-Semerena (1996) J. Bacteriol. 178:7016-7019; Alternative locus ID: PMED4_12181. | 0.984 |
CobN | cobD | PMM0879 | PMM1316 | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | Putative cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.575 |
CobN | cobO | PMM0879 | PMM0523 | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | Possible cob(I)alamin adenosyltransferase; Citation: Lundrigan and Kadner (1989) J. Bacteriol. 171:154-161; Fonseca and Escalente-Semerena (2001) J. Biol. Chem. 276:32101-32108; Alternative locus ID: PMED4_05721. | 0.967 |
CobN | cobU/cobP | PMM0879 | PMM0863 | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | Putative cobinamide kinase; Citation: O'Toole and Excalante-Semerena (1995) J. Biol. Chem. 270:23560-23569; Thomas et al. (2000) J. Biol. Chem. 275:27576-27586; Alternative locus ID: PMED4_09731. | 0.757 |
CobS | CobN | PMM0270 | PMM0879 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | 0.789 |
CobS | PMM0245 | PMM0270 | PMM0245 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | cob(I)alamin adenosyltransferase; Alternative locus ID: PMED4_02501. | 0.917 |
CobS | PMM1570 | PMM0270 | PMM1570 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Alternative locus ID: PMED4_17801. | 0.935 |
CobS | cbiA,cobB | PMM0270 | PMM1072 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Putative Cobyrinic acid a,c-diamide synthase; BELONGS TO THE SIRTUIN FAMILY; Citation: Tsang and Escalante-Semerena (1996) J. Bacteriol. 178:7016-7019; Alternative locus ID: PMED4_12181. | 0.805 |
CobS | cobB | PMM0270 | PMM1160 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Cobyric acid synthase CobB; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.914 |
CobS | cobD | PMM0270 | PMM1316 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Putative cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.908 |
CobS | cobO | PMM0270 | PMM0523 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Possible cob(I)alamin adenosyltransferase; Citation: Lundrigan and Kadner (1989) J. Bacteriol. 171:154-161; Fonseca and Escalente-Semerena (2001) J. Biol. Chem. 276:32101-32108; Alternative locus ID: PMED4_05721. | 0.958 |
CobS | cobU/cobP | PMM0270 | PMM0863 | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Putative cobinamide kinase; Citation: O'Toole and Excalante-Semerena (1995) J. Biol. Chem. 270:23560-23569; Thomas et al. (2000) J. Biol. Chem. 275:27576-27586; Alternative locus ID: PMED4_09731. | 0.991 |
PMM0243 | PMM0245 | PMM0243 | PMM0245 | Possible Thy1 protein homolog; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | cob(I)alamin adenosyltransferase; Alternative locus ID: PMED4_02501. | 0.829 |
PMM0243 | dcd | PMM0243 | PMM0244 | Possible Thy1 protein homolog; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | dCTP Deaminase; Alternative locus ID: PMED4_02491. | 0.875 |
PMM0245 | CobN | PMM0245 | PMM0879 | cob(I)alamin adenosyltransferase; Alternative locus ID: PMED4_02501. | Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. | 0.904 |
PMM0245 | CobS | PMM0245 | PMM0270 | cob(I)alamin adenosyltransferase; Alternative locus ID: PMED4_02501. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.917 |
PMM0245 | PMM0243 | PMM0245 | PMM0243 | cob(I)alamin adenosyltransferase; Alternative locus ID: PMED4_02501. | Possible Thy1 protein homolog; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.829 |