| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PMM0261 | manC | PMM0261 | PMM1196 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.490 |
| PMM0261 | mraY | PMM0261 | PMM1709 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.409 |
| PMM0261 | murB | PMM0261 | PMM0021 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.496 |
| PMM0261 | murC | PMM0261 | PMM0022 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Probable UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.455 |
| PMM0261 | murD | PMM0261 | PMM1364 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.487 |
| PMM0261 | murE | PMM0261 | PMM0413 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.444 |
| PMM0261 | murF | PMM0261 | PMM0610 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Cytoplasmic peptidoglycan synthetase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.508 |
| PMM0261 | murG | PMM0261 | PMM0197 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.485 |
| PMM0261 | putative | PMM0261 | PMM1300 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | UDP-N-glucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.620 |
| PMM0261 | sfsA | PMM0261 | PMM0262 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Putative sugar fermentation stimulation protein; Alternative locus ID: PMED4_02671; Belongs to the SfsA family. | 0.669 |
| manC | PMM0261 | PMM1196 | PMM0261 | GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family. | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | 0.490 |
| manC | mraY | PMM1196 | PMM1709 | GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family. | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.473 |
| mraY | PMM0261 | PMM1709 | PMM0261 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | 0.409 |
| mraY | manC | PMM1709 | PMM1196 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.473 |
| mraY | murB | PMM1709 | PMM0021 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.771 |
| mraY | murC | PMM1709 | PMM0022 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Probable UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.875 |
| mraY | murD | PMM1709 | PMM1364 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.944 |
| mraY | murE | PMM1709 | PMM0413 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.877 |
| mraY | murF | PMM1709 | PMM0610 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Cytoplasmic peptidoglycan synthetase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.991 |
| mraY | murG | PMM1709 | PMM0197 | Putative phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.986 |