| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PMM0261 | manC | PMM0261 | PMM1196 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.555 |
| PMM0261 | murB | PMM0261 | PMM0021 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.521 |
| PMM0261 | murC | PMM0261 | PMM0022 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Probable UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.480 |
| PMM0261 | murD | PMM0261 | PMM1364 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.548 |
| PMM0261 | murE | PMM0261 | PMM0413 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.591 |
| PMM0261 | murF | PMM0261 | PMM0610 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Cytoplasmic peptidoglycan synthetase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.543 |
| PMM0261 | murG | PMM0261 | PMM0197 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.580 |
| PMM0261 | putative | PMM0261 | PMM1300 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | UDP-N-glucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.593 |
| PMM0261 | rodA | PMM0261 | PMM1580 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Peptidoglycan glycosyltransferase RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.529 |
| PMM0261 | sfsA | PMM0261 | PMM0262 | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | Putative sugar fermentation stimulation protein; Alternative locus ID: PMED4_02671; Belongs to the SfsA family. | 0.644 |
| manC | PMM0261 | PMM1196 | PMM0261 | GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family. | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | 0.555 |
| manC | putative | PMM1196 | PMM1300 | GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-N-glucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.835 |
| murB | PMM0261 | PMM0021 | PMM0261 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Conserved hypothetical protein; Alternative locus ID: PMED4_02661. | 0.521 |
| murB | murC | PMM0021 | PMM0022 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Probable UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
| murB | murD | PMM0021 | PMM1364 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.974 |
| murB | murE | PMM0021 | PMM0413 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.925 |
| murB | murF | PMM0021 | PMM0610 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Cytoplasmic peptidoglycan synthetase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.959 |
| murB | murG | PMM0021 | PMM0197 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.958 |
| murB | putative | PMM0021 | PMM1300 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-glucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.986 |
| murB | rodA | PMM0021 | PMM1580 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Peptidoglycan glycosyltransferase RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.638 |