Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PMM0278Phosphotransferase superclass; Alternative locus ID: PMED4_02831. (486 aa)    
Predicted Functional Partners:
dacA
Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
 
 
 0.824
PMM0279
Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.819
manC
GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.653
PMM0277
Conserved hypothetical protein; Alternative locus ID: PMED4_02821.
       0.636
pykF
Pyruvate kinase; Alternative locus ID: PMED4_10231; Belongs to the pyruvate kinase family.
  
  
 0.561
PMM1225
Conserved hypothetical protein; Alternative locus ID: PMED4_13901.
  
  
 0.484
guaB
Putative IMP dehydrogenase; Alternative locus ID: PMED4_12081.
 
 
 0.474
panC,
Putative bifunctional enzyme; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
  
  
 0.462
PMM1701
Putative chloride channel; Alternative locus ID: PMED4_19121.
     
 0.423
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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