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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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[Homology]
Score
thiDPhosphomethylpyrimidine kinase; Citation: Peterson and Downs (1997) J. Bacteriol. 179:4894-4900; Alternative locus ID: PMED4_03821. (262 aa)    
Predicted Functional Partners:
PMM0357
TENA/THI-4 protein; Alternative locus ID: PMED4_03811.
 
 0.999
thiE
Thiamine monophosphate synthase (TMP); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
 0.999
thiC
ThiC family; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
 
 0.991
thiG
Thiamin biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.966
moeB
Molybdopterin biosynthesis protein; BELONGS TO THE HESA/MOEB/THIF FAMILY; Citation: Nohno et al (1988) J. Bacteriol. 170:4097-4102; Alternative locus ID: PMED4_17791.
  
  
 0.832
PMM1275
DUF170; Alternative locus ID: PMED4_14411.
  
  
 0.813
PMM1101
Putative ATP-dependent RNA helicase; Alternative locus ID: PMED4_12471; Belongs to the DEAD box helicase family.
 
 
    0.750
hli15
Possible high light inducible protein; Has EXXNGXXAMXG motif; Citation: Bhaya et al. (2002) FEMS Microbiol Lett 215:209-219; Alternative locus ID: PMED4_12761.
      
 0.718
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
  
 0.607
hli22
Possible high light inducible protein; Has EXXNGXXAMXG motif; Citation: Bahya, D. et al. 2002. Analysis of the hli gene family in marine and freshwater cyanobacteria FEMS Microbiol Lett In Press; Alternative locus ID: PMED4_07541.
      
 0.492
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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