Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
proCDelta 1-pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)    
Predicted Functional Partners:
proB
Putative glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.951
PMM0356
Proline iminopeptidase; Alternative locus ID: PMED4_03791; Belongs to the peptidase S33 family.
     
  0.900
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.877
sepF
Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
     
 0.839
pyrR
Phosphoribosyl transferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
 
   
 0.735
glsF,
Ferredoxin-dependent glutamate synthase, Fd-GOGAT; Alternative locus ID: PMED4_17221.
     
 0.642
PMM0394
Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.611
PMM0393
Conserved hypothetical protein; Alternative locus ID: PMED4_04341.
   
 
 0.598
PMM0392
Possible cobalt transport protein; Alternative locus ID: PMED4_04331.
  
  
 0.597
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.596
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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