STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xthAExodeoxyribonuclease III; Alternative locus ID: PMED4_05331. (281 aa)    
Predicted Functional Partners:
nth
Putative endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.988
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.934
rsuA
Putative pseudouridylate synthase specific to ribosomal small subunit; Alternative locus ID: PMED4_07111; Belongs to the pseudouridine synthase RsuA family.
  
    0.812
lig
ATP-dependent DNA ligase; Alternative locus ID: PMED4_18901.
 
 
 0.747
pyrH,smbA
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.741
holB
DNA polymerase III, delta prime subunit; Alternative locus ID: PMED4_01351.
   
 0.707
PMM0729
Possible ATP-dependent DNA ligase; Alternative locus ID: PMED4_08061.
  
 
 0.707
PMM0234
Possible Methylpurine-DNA glycosylase (MPG); Alternative locus ID: PMED4_02391; Belongs to the DNA glycosylase MPG family.
   
 
 0.692
PMM0485
Conserved hypothetical protein; Alternative locus ID: PMED4_05341.
  
    0.665
PMM0918
Putative cytidine/deoxycytidylate deaminase; Alternative locus ID: PMED4_10291.
   
 
 0.627
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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