STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purA,adeKAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (436 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase; Frameshift; similar to P9515_16441; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.996
guaB
Putative IMP dehydrogenase; Alternative locus ID: PMED4_12081.
  
 
 0.990
purH
AICARFT/IMPCHase bienzyme:Methylglyoxal synthase-like domain; Alternative locus ID: PMED4_02711.
  
 0.982
pyrB
Aspartate carbamoyltransferase; Putative assignment; Alternative locus ID: PMED4_02381; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.936
argG
Argininosuccinate synthase; Alternative locus ID: PMED4_19181; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
 0.934
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 
 0.926
aspC
Aminotransferases class-I; Possible role in phosphonate metabolism; Alternative locus ID: PMED4_07301.
   
 0.911
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.910
PMM0222
Putative assignment; Alternative locus ID: PMED4_02271; Belongs to the AspA/AstE family. Aspartoacylase subfamily.
     
  0.900
PMM0821
Conserved hypothetical protein; Alternative locus ID: PMED4_09151.
   
 
  0.900
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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