Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobCPossible alpha-ribazole-5'-P phosphatase; Phosphatase involved in the assembly of the nucleotide loop of cobalamin; Citation: O'Toole et al. (1994) J. Biol. Chem. 269:26503-26511; Alternative locus ID: PMED4_05641; Belongs to the phosphoglycerate mutase family. (442 aa)    
Predicted Functional Partners:
PMM0514
Putative dihydroorotase; Alternative locus ID: PMED4_05631.
       0.815
glyA
Serine hydroxymethyltransferase (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.674
PMM0516
Possible membrane associated protease; Alternative locus ID: PMED4_05651.
  
    0.633
DHSS
Soluble hydrogenase small subunit; BELONGS TO CLASS-V OF PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASES; Alternative locus ID: PMED4_00341.
 
 
  0.577
cbiG/cobJ
Bifunctional cbiH protien and PRECORRIN-3B C17-METHYLTRANSFERASE; Citation: Debussche et al. (1993) J. Bacteriol. 175:7430-7440; Roth et al. (1993) J. Bacteriol. 175:3303-3316; Alternative locus ID: PMED4_17351.
  
  
 0.567
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
 
  
 0.565
glsF,
Ferredoxin-dependent glutamate synthase, Fd-GOGAT; Alternative locus ID: PMED4_17221.
     
 0.558
pykF
Pyruvate kinase; Alternative locus ID: PMED4_10231; Belongs to the pyruvate kinase family.
     
 0.534
ftsI
Putative peptidoglycan synthetase (pbp transpeptidase domain); Alternative locus ID: PMED4_05671.
       0.512
PMM0517
Hypothetical protein; Alternative locus ID: PMED4_05661.
       0.509
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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