STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpFPhosphoribosylanthranilate isomerase; Alternative locus ID: PMED4_05861; Belongs to the TrpF family. (220 aa)    
Predicted Functional Partners:
trpC
Indole-3-glycerol phosphate synthase; Putative assignment; Alternative locus ID: PMED4_14631; Belongs to the TrpC family.
 
 0.999
trpD/G
Putative Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.998
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.990
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.971
pabA
Para-aminobenzoate synthase component II; CONTAINS 1 TYPE-1 GLUTAMINE AMIDOTRANSFERASE DOMAIN; Citation: Kapland and Nichols (1983) J. Mol. Biol. 168:451-468; Tran et al. (1990) J. Bacteriol. 172:397-410; Alternative locus ID: PMED4_01901.
 
  
 0.928
trpE
Anthranilate synthase component I and chorismate binding enzyme; Definite assignment; Alternative locus ID: PMED4_17871.
 
  
 0.855
PMM1692
Possible p-aminobenzoate synthetase; Citation: Goncharodd and Nichols (1984) J. Bacteriol. 159:57-62; Alternative locus ID: PMED4_19031.
 
  
 0.784
hisA
PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE; Alternative locus ID: PMED4_08821.
  
  
 0.682
hisI
Phosphoribosyl-AMP cyclohydrolase; Alternative locus ID: PMED4_06271; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.681
PMM0538
Conserved hypothetical protein; Alternative locus ID: PMED4_05871.
  
    0.666
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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