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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (349 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; Putative assignment; Alternative locus ID: PMED4_02381; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.979
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.977
PMM0514
Putative dihydroorotase; Alternative locus ID: PMED4_05631.
    
 0.910
carB
Carbamoyl-phosphate synthase, large subunit; Alternative locus ID: PMED4_09191; Belongs to the CarB family.
   
  
 0.665
carA,
STAS domain:Anti-sigma factor antagonist; Alternative locus ID: PMED4_10606; Belongs to the CarA family.
   
  
 0.641
PMM0568
Putative CaCA family sodium/calcium exchanger; Alternative locus ID: PMED4_06171.
  
    0.561
ndhL
NADH dehydrogenase subunit NdhL (ndhL); NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
       0.508
PMM0571
Conserved hypothetical protein; Alternative locus ID: PMED4_06201.
       0.508
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
       0.465
purF
Glutamine amidotransferase class-II:Phosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
    0.410
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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