STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMM0579Conserved hypothetical protein; Alternative locus ID: PMED4_06281. (154 aa)    
Predicted Functional Partners:
queE
Possible organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.965
folE
Putative GTP cyclohydrolase I; Citation: Katzenmeier et al. (1991) Biol. Chem. Hoppe-Seyler 372:991-997; Alternative locus ID: PMED4_05851.
  
 
 0.944
PMM0106
6-pyruvoyl tetrahydropterin synthase; Alternative locus ID: PMED4_01121.
   
 
  0.900
queC
Hypothetical ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
  
 0.806
hisI
Phosphoribosyl-AMP cyclohydrolase; Alternative locus ID: PMED4_06271; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.792
PMM0600
Conserved hypothetical protein; Alternative locus ID: PMED4_06491.
  
    0.733
PMM1047
Conserved hypothetical protein; Alternative locus ID: PMED4_11931.
  
    0.704
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.590
PMM1677
Conserved hypothetical protein; Alternative locus ID: PMED4_18881; Belongs to the SprT family.
  
    0.563
PMM0795
Conserved hypothetical protein; Alternative locus ID: PMED4_08811.
  
    0.531
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.