Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sdsPolyprenyl synthetase; Alternative locus ID: PMED4_06671; Belongs to the FPP/GGPP synthase family. (323 aa)    
Predicted Functional Partners:
crtE
Polyprenyl synthetase; Alternative locus ID: PMED4_12161; Belongs to the FPP/GGPP synthase family.
  
  
 
0.916
ubiA
Probable 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of plastoquinone-9 (PQ-9) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 4-hydroxy-3-solanesylbenzoate. Belongs to the UbiA prenyltransferase family.
 
 
 0.910
chlP
Aromatic-ring hydroxylase (flavoprotein monooxygenase); Alternative locus ID: PMED4_08451.
  
 0.909
crtB,pys
Squalene and phytoene synthases; Alternative locus ID: PMED4_01491.
  
 0.893
menA
1,4-dihydroxy-2-naphthoate (DHNA) octaprenyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.
 
  
 0.857
murI
Putative aspartate and glutamate racemases:Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
  
  
 0.772
uppS
Undecaprenyl pyrophosphate synthetase (UPPS); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
  
 0.763
PMM0615
Possible nitrilase; Alternative locus ID: PMED4_06641.
       0.745
PMM0616
Cell wall hydrolase/autolysin; Alternative locus ID: PMED4_06651.
       0.745
PMM0614
Conserved hypothetical protein; Probable pseudogene due to N-terminal truncation - MIT9313 and WH8102 have a longer form (with other homologs) and also have an additional gene upstream before aroA; Alternative locus ID: PMED4_06631; Belongs to the ComB family.
  
    0.677
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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