Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnaQPossible DNA polymerase III, epsilon subunit; Alternative locus ID: PMED4_06701. (270 aa)    
Predicted Functional Partners:
dnaE
DNA polymerase III, alpha subunit; Alternative locus ID: PMED4_10561.
   
 0.972
dnaX
DNA polymerase, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.951
PMM1647
Conserved hypothetical protein; Alternative locus ID: PMED4_18571.
    
 0.923
holB
DNA polymerase III, delta prime subunit; Alternative locus ID: PMED4_01351.
    
  0.917
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
     
  0.900
rnhA
Possible ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.873
PMM0620
Conserved hypothetical protein; Alternative locus ID: PMED4_06691.
 
     0.695
PMM1047
Conserved hypothetical protein; Alternative locus ID: PMED4_11931.
  
     0.667
PMM0600
Conserved hypothetical protein; Alternative locus ID: PMED4_06491.
  
    0.582
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.565
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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