| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PMM0408 | ahcY, | PMM0408 | PMM1625 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.914 |
| PMM0408 | cysD-2 | PMM0408 | PMM0642 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative O-Acetyl homoserine sulfhydrylase; Alternative locus ID: PMED4_06921. | 0.937 |
| PMM0408 | cysK1 | PMM0408 | PMM0407 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_04501; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.980 |
| PMM0408 | cysK2 | PMM0408 | PMM0123 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_01291; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.949 |
| PMM0408 | metA | PMM0408 | PMM0643 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.943 |
| PMM0408 | metH | PMM0408 | PMM0877 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Putative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.970 |
| PMM0408 | thrA,hom | PMM0408 | PMM1051 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Homoserine dehydrogenase:ACT domain; Putative assignment; Alternative locus ID: PMED4_11971. | 0.864 |
| PMM0408 | thrB | PMM0408 | PMM0595 | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | Homoserine kinase:GHMP kinases putative ATP-binding domain; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.826 |
| ahcY, | PMM0408 | PMM1625 | PMM0408 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | 0.914 |
| ahcY, | cysD-2 | PMM1625 | PMM0642 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Putative O-Acetyl homoserine sulfhydrylase; Alternative locus ID: PMED4_06921. | 0.911 |
| ahcY, | cysK1 | PMM1625 | PMM0407 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_04501; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.837 |
| ahcY, | cysK2 | PMM1625 | PMM0123 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_01291; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.836 |
| ahcY, | metH | PMM1625 | PMM0877 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Putative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.964 |
| ahcY, | metK | PMM1625 | PMM0311 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.925 |
| ahcY, | thrA,hom | PMM1625 | PMM1051 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Homoserine dehydrogenase:ACT domain; Putative assignment; Alternative locus ID: PMED4_11971. | 0.814 |
| ahcY, | thrB | PMM1625 | PMM0595 | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Homoserine kinase:GHMP kinases putative ATP-binding domain; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.806 |
| cysD-2 | PMM0408 | PMM0642 | PMM0408 | Putative O-Acetyl homoserine sulfhydrylase; Alternative locus ID: PMED4_06921. | Possible Cystathionine gamma-synthase; Alternative locus ID: PMED4_04511. | 0.937 |
| cysD-2 | ahcY, | PMM0642 | PMM1625 | Putative O-Acetyl homoserine sulfhydrylase; Alternative locus ID: PMED4_06921. | Putative adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.911 |
| cysD-2 | cysK1 | PMM0642 | PMM0407 | Putative O-Acetyl homoserine sulfhydrylase; Alternative locus ID: PMED4_06921. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_04501; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.830 |
| cysD-2 | cysK2 | PMM0642 | PMM0123 | Putative O-Acetyl homoserine sulfhydrylase; Alternative locus ID: PMED4_06921. | O-acetylserine (thiol)-lyase A; Alternative locus ID: PMED4_01291; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.830 |