Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
phoBTwo-component response regulator, phosphate; Alternative locus ID: PMED4_07791. (242 aa)    
Predicted Functional Partners:
phoR
Two-component sensor histidine kinase, phosphate sensing; Alternative locus ID: PMED4_07801.
 0.999
nblS
Two-component sensor histidine kinase; Alternative locus ID: PMED4_15091.
 
 
 0.848
sasA
Two-component sensor histidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
 
 
 0.838
pstA,phoT
Putative phosphate ABC transporter; Alternative locus ID: PMED4_08001.
     
 0.806
pstB
Putative phosphate ABC transporter, ATP binding subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.732
hli16
Possible high light inducible protein; Has EXXNGXXAMXG motif; Citation: Bhaya et al. (2002) FEMS Microbiol Lett 215:209-219; Alternative locus ID: PMED4_09101.
      
 0.613
rpoA
Bacterial RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.567
glsF,
Ferredoxin-dependent glutamate synthase, Fd-GOGAT; Alternative locus ID: PMED4_17221.
      
 0.556
som
Possible porin; Alternative locus ID: PMED4_07831; Belongs to the OprB family.
      
 0.533
rpoC1
RNA polymerase gamma subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.520
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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