Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpX,Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bisphosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. (333 aa)    
Predicted Functional Partners:
tktA,
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 
 
 0.989
CbbA
Fructose-bisphosphate/sedoheptulose-1, 7-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.969
pgi
Phosphoglucose isomerase (PGI); Alternative locus ID: PMED4_10011.
   
 
 0.939
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
    
 0.927
PMM1235
Possible N-terminal fragment of transketolase; Alternative locus ID: PMED4_14001.
 
 
 
  0.913
PMM1627
Putative carbohydrate kinase; Alternative locus ID: PMED4_18371.
    
 0.910
PMM1236
Unknown; Alternative locus ID: PMED4_14011.
     
  0.900
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
    0.778
glgC
ADP-glucose pyrophosphorylase; Alternative locus ID: PMED4_08541; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
     
 0.775
rpe,
Ribulose-phosphate 3-epimerase; Alternative locus ID: PMED4_08511.
  
  
 0.718
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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