Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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nthPutative endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (217 aa)    
Predicted Functional Partners:
xthA
Exodeoxyribonuclease III; Alternative locus ID: PMED4_05331.
 
 0.991
ycf39
Conserved hypothetical protein; Alternative locus ID: PMED4_08871.
  
   0.737
PMM1571
Conserved hypothetical protein; Alternative locus ID: PMED4_17811.
 
    0.716
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.711
lig
ATP-dependent DNA ligase; Alternative locus ID: PMED4_18901.
  
  
 0.694
futC,
ABC transporter, ATP binding component, possibly iron transporter; Alternative locus ID: PMED4_08891.
       0.636
PMM0800
Conserved hypothetical protein; Alternative locus ID: PMED4_08861.
       0.611
rpsT,rps20
30s Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
      
 0.543
rnz
Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
     
 0.528
rpl35,
50S ribosomal protein L35; Alternative locus ID: PMED4_18711; Belongs to the bacterial ribosomal protein bL35 family.
   
  
 0.502
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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