Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tpi,Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (230 aa)    
Predicted Functional Partners:
gap2
Glyceraldehyde 3-phosphate dehydrogenase(NADP+)(phosphorylating); Citation: AJ245541; Mol Biol Evol 2001 Dec;18(12):2240-2249; Alternative locus ID: PMED4_00221; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.999
pgk,
Phosphoglycerate kinase; Alternative locus ID: PMED4_02011; Belongs to the phosphoglycerate kinase family.
 
 0.999
pgi
Phosphoglucose isomerase (PGI); Alternative locus ID: PMED4_10011.
 
 0.996
gap1
Putative glyceraldehyde 3-phosphate dehydrogenase; Alternative locus ID: PMED4_07871; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.995
CbbA
Fructose-bisphosphate/sedoheptulose-1, 7-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 0.987
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.982
tktA,
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.979
pykF
Pyruvate kinase; Alternative locus ID: PMED4_10231; Belongs to the pyruvate kinase family.
 
 
 0.963
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.948
PMM1236
Unknown; Alternative locus ID: PMED4_14011.
 
  
  0.911
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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