STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpxThioredoxin peroxidase; Alternative locus ID: PMED4_09521. (194 aa)    
Predicted Functional Partners:
PMM1150
Putative thioredoxin reductase; Alternative locus ID: PMED4_13081.
  
 
 0.988
txlA
Thioredoxin-like protein TxlA; Alternative locus ID: PMED4_02471.
  
 0.897
PMM0794
Conserved hypothetical protein; Alternative locus ID: PMED4_08801.
  
 0.885
rub
Probable rubredoxin; Alternative locus ID: PMED4_03001.
  
  
 0.858
PMM1006
Glutathione peroxidase; Alternative locus ID: PMED4_11341; Belongs to the glutathione peroxidase family.
   
 
 0.848
trxB
FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Alternative locus ID: PMED4_02171.
  
 
 0.842
PMM1901
Conserved hypothetical protein; Alternative locus ID: PMED4_09531.
       0.653
PMM0804
Ferritin; Iron-storage protein.
  
  
 0.596
PMM0043
Flavoprotein; Alternative locus ID: PMED4_00431.
  
  
 0.561
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
   
 
 0.552
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.