node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
guaA | ileS | PMM0037 | PMM0238 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.663 |
guaA | leuS | PMM0037 | PMM0889 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | Leucyl-tRNA synthetase; Alternative locus ID: PMED4_10001; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.495 |
guaA | metG | PMM0037 | PMM0867 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.623 |
guaA | pheS | PMM0037 | PMM1270 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phenylalanyl-tRNA synthetase alpha chain; Putative assignment; Alternative locus ID: PMED4_14361; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.582 |
guaA | pheT | PMM0037 | PMM0871 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phenylalanyl-tRNA synthetase beta chain; Putative assignment; Alternative locus ID: PMED4_09811; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.919 |
guaA | pyrD | PMM0037 | PMM0199 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.656 |
guaA | rpoB | PMM0037 | PMM1485 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.892 |
guaA | rps2, | PMM0037 | PMM0753 | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S2; Alternative locus ID: PMED4_08381; Belongs to the universal ribosomal protein uS2 family. | 0.667 |
ileS | guaA | PMM0238 | PMM0037 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.663 |
ileS | leuS | PMM0238 | PMM0889 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Leucyl-tRNA synthetase; Alternative locus ID: PMED4_10001; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.905 |
ileS | metG | PMM0238 | PMM0867 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.870 |
ileS | pheS | PMM0238 | PMM1270 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Phenylalanyl-tRNA synthetase alpha chain; Putative assignment; Alternative locus ID: PMED4_14361; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.546 |
ileS | pheT | PMM0238 | PMM0871 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Phenylalanyl-tRNA synthetase beta chain; Putative assignment; Alternative locus ID: PMED4_09811; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.984 |
ileS | rpoB | PMM0238 | PMM1485 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.483 |
ileS | tyrS | PMM0238 | PMM1329 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.630 |
leuS | guaA | PMM0889 | PMM0037 | Leucyl-tRNA synthetase; Alternative locus ID: PMED4_10001; Belongs to the class-I aminoacyl-tRNA synthetase family. | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.495 |
leuS | ileS | PMM0889 | PMM0238 | Leucyl-tRNA synthetase; Alternative locus ID: PMED4_10001; Belongs to the class-I aminoacyl-tRNA synthetase family. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.905 |
leuS | metG | PMM0889 | PMM0867 | Leucyl-tRNA synthetase; Alternative locus ID: PMED4_10001; Belongs to the class-I aminoacyl-tRNA synthetase family. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.961 |
leuS | pheS | PMM0889 | PMM1270 | Leucyl-tRNA synthetase; Alternative locus ID: PMED4_10001; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phenylalanyl-tRNA synthetase alpha chain; Putative assignment; Alternative locus ID: PMED4_14361; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.624 |
leuS | pheT | PMM0889 | PMM0871 | Leucyl-tRNA synthetase; Alternative locus ID: PMED4_10001; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phenylalanyl-tRNA synthetase beta chain; Putative assignment; Alternative locus ID: PMED4_09811; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.990 |