STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CobNCobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901. (1245 aa)    
Predicted Functional Partners:
cbiA,cobB
Putative Cobyrinic acid a,c-diamide synthase; BELONGS TO THE SIRTUIN FAMILY; Citation: Tsang and Escalante-Semerena (1996) J. Bacteriol. 178:7016-7019; Alternative locus ID: PMED4_12181.
 
 
 0.984
cobO
Possible cob(I)alamin adenosyltransferase; Citation: Lundrigan and Kadner (1989) J. Bacteriol. 171:154-161; Fonseca and Escalente-Semerena (2001) J. Biol. Chem. 276:32101-32108; Alternative locus ID: PMED4_05721.
 
 0.967
chlD
Protoporphyrin IX Magnesium chelatase, ChlD subunit; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
 
 
 0.943
cobI/cbiL
PRECORRIN-2 C20-METHYLTRANSFERASE; Cobalamin biosynthesis; Citation: Crouzet et al. (1990) J. Bacteriol. 172:5980-5990; Roth et al. (1993) J. Bacteriol. 175:3303-3316; Alternative locus ID: PMED4_04301; Belongs to the precorrin methyltransferase family.
 
  
 0.918
cobL
Putative precorrin-6y methylase; Citation: Blanche et al. (1992) J. Bacteriol. 174:1050-1052; Alternative locus ID: PMED4_14341.
 
  
 0.905
PMM0245
cob(I)alamin adenosyltransferase; Alternative locus ID: PMED4_02501.
    
 0.904
PMM1570
ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Alternative locus ID: PMED4_17801.
    
 0.904
hupE
Putative hydrogenase accessory protein; Alternative locus ID: PMED4_12701.
      
 0.851
chlI
Protoporphyrin IX Magnesium chelatase, ChlI subunit; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
 
  
 0.844
CobS
Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
  
 0.789
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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